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Nucleic acids are remarkable molecules. In addition to Watson–Crick base pairing, the different structural motifs of these molecules can bind non‐nucleic acid targets or catalyze chemical reactions. Additionally, nucleic acids are easily modified with different molecules or functional groups. These properties make nucleic acids, particularly DNA, ideally suited for use in electrochemical biosensors,...
Nucleic acids are remarkable molecules. In addition to Watson–Crick base pairing, the different structural motifs of these molecules can bind non‐nucleic acid targets or catalyze chemical reactions. Additionally, nucleic acids are easily modified with different molecules or functional groups. These properties make nucleic acids, particularly DNA, ideally suited for use in electrochemical biosensors,...
Molecular imprinting refers to templated polymerization with rationally designed monomers, and this is a general method to prepare stable and cost‐effective ligands. This attractive concept however suffers from low affinity, low specificity, and limited signaling mechanisms for binding. Acrydite‐modified DNA oligonucleotides can be readily copolymerized into acrylic polymers. With molecular recognition...
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