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As severe acute respiratory syndrome coronavirus‐2 (SARS‐CoV‐2) mutates continually, the current vaccines are unable to provide sufficient protection. It is important to develop a broad‐spectrum vaccine with conserved antigens to prevent variant infection. Here we fused the SARS‐CoV‐2 N protein with Helicobacter pylori nonheme ferritin to construct a SARS‐CoV‐2 N‐Ferritin nanoparticle vaccine. Compared...