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Noninvasive therapeutic cell tracking methods in living animals are important for understanding cell function and fate in connection with cell therapy. Here we report a new particle system based on chitosan-coated poly(lactic-co-glycolic acid) perfluorooctyl bromide (PLGA PFOB) nanoparticles designed for 19F magnetic resonance imaging (MRI) cell tracking. Chitosan was adsorbed onto the PLGA PFOB nanoparticles...
A novel amphiphilic chitosan derivative, acryloyl chitosan (AcCs), was synthesized by a homogeneous reaction of chitosan and acryloyl chloride using methanesulfonic acid as solvent and catalyst. The concentrated solutions of AcCs/acrylic acid were investigated by polarized optical microscopy (POM) and found demonstrate cholesteric mesophase above the critical concentration of 45wt%. AcCs/polyacrylic...
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