The Infona portal uses cookies, i.e. strings of text saved by a browser on the user's device. The portal can access those files and use them to remember the user's data, such as their chosen settings (screen view, interface language, etc.), or their login data. By using the Infona portal the user accepts automatic saving and using this information for portal operation purposes. More information on the subject can be found in the Privacy Policy and Terms of Service. By closing this window the user confirms that they have read the information on cookie usage, and they accept the privacy policy and the way cookies are used by the portal. You can change the cookie settings in your browser.
We describe a technology combining nanopore fluidic with surface enhanced Raman spectroscopy (SERS) for real-time, single molecule detection. After optimization of both optical and device design, we can control the nanopore like a valve for molecule motions and detect a single nucleotide even at 10 ms.
Raman spectroscopy is a widely used vibrational spectroscopic technique to identify and study chemical compounds. The signal can be strongly enhanced in the presence of metal nanostructures resulting in so-called surface-enhanced Raman scattering (SERS). Here, we describe the use of SERS for the molecular characterization of DNA molecules inside a nanoslit across a thin, metal-coated membrane. Nanoslits...
Set the date range to filter the displayed results. You can set a starting date, ending date or both. You can enter the dates manually or choose them from the calendar.