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Researchers have debated whether regulation of the COX enzymes (COX-1 and COX-2), which mediate production of prostaglandins (PGs), affects the pathogenesis of nasal polyps (NPs) and aspirin-intolerant asthma (AIA).We investigated the roles of PGE 2 , COX-1 and COX-2, and PGE 2 receptors in the development of NPs and AIA by measuring their expression in fibroblasts derived from nasal...
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