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Low frequency stimulation (LFS) has an inhibitory effect on kindling acquisition. In the present study the effect of the perforant path LFS on induction of rapid perforant path kindled seizures and synaptic transmission in the dentate gyrus was investigated. Animals were kindled by perforant path stimulation in a rapid kindling manner (12 stimulations per day). In one group of animals LFS (0.1ms pulse...
In this study the effect of adenosine A 1 receptors of the entorhinal cortex (EC) and amygdala on kindled seizures was investigated. Animals were kindled by daily electrical stimulation of amygdala (group 1) or EC (group 2). In the fully kindled animals, N 6 -cyclohexyladenosine (CHA), a selective A 1 receptor agonist, and 1,3-dimethyl-8-cyclopenthylxanthine (CPT), a selective...
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