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Recently, great efforts have been made to use biosensors for the early diagnosis of cancer. Specifically, using a biomarker to detect H2O2 in physiological conditions is of great significance for understanding the signal transduction pathways and achieving early cancer diagnosis. In this work, we report an innovative H2O2 sensor that was fabricated by trimetallic AuPtPd nanocomposites platform on...
Active proteins play important roles in the function regulation of human bodies and attract much interest for use in pharmaceuticals and clinical diagnostics. However, the lack of primary methods to analyze active proteins means there is currently no metrology standard for active protein measurement. In recent years, calibration-free concentration analysis (CFCA), which is based on surface plasmon...
Magnetic polymer particles with different surface functionalizations were prepared by a simple one-pot solvothermal method and characterized as peroxidase mimetics. The fluorescence enhancement obtained by attaching a β-cyclodextrin polymer (Pβ-CD) to the surfaces of Fe3O4 magnetic microspheres (Fe3O4 MMs) to generate a Fe3O4/Pβ-CD composite allowed the rapid, sensitive and selective analysis of glucose...
Enzyme mimetics have recently attracted considerable interest because of their high stability and low cost. We developed a general H 2 O 2 -involved fluorescence system using Fe 3 O 4 magnetic microspheres as peroxidase mimetics and benzoic acid (BA) as indicator. Glucose and p-nitrophenol were used as models to determine the characteristics and effectiveness of the...
Precise measurement for the purity of organic compounds will fundamentally improve the capabilities and measurement services of the organic chemical analysis. Quantitative nuclear magnetic resonance (qNMR) is an important method to assess the purity of organic compounds. We presented a precise measurement method for the purity of small molecule with identification of impurities. In addition, the qNMR...
Folic acid is one of the most important nutrient substances for human beings, especially for the pregnant women and infants. Therefore the purity determination of folic acid is particularly important. The mass balance method was employed to determine the purity of folic acid, by using the measures of high performance liquid chromatography (HPLC), Karl Fischer titration and other conventional approach...
Peroxymonocarbonate (HCO 4− ) was produced by the online reaction of bicarbonate with hydrogen peroxide. A strong chemiluminescence (CL) was observed when HCO 4− reacted with AuCl 4− without any special CL reagent. When bisphenol A (BPA) was added to AuCl 4− –HCO 4− CL system, the CL emission was inhibited significantly. This new CL...
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