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Key points
This study assessed the dynamic response of global cerebral blood flow (CBF) and cerebral fuel utilization during and following incremental supine exercise to exhaustion.
Global CBF increased more during exercise and recovery at high altitude (HA) compared with sea level (SL) such that cerebral oxygen delivery () was maintained.
The increase in cerebral metabolic rate of oxygen during...
• The partial pressures of arterial carbon dioxide () and oxygen () has a marked influence on brain blood flow.
• It is unclear if the larger brain arteries are also sensitive to changing and and if different areas of the brain possess different sensitivities.
• We separately altered and and measured the diameter and blood flow in the main arteries delivering blood to the cortex and brainstem...
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