Search results for: Xiang Zuo

Items from 1 to 20 out of 39 results

article

P‐15.20: Influence of OLED Touch Metal Mesh on Optical Performance

Ke Ding, Xiang Zuo, SiMin Peng, Jing Ni, more

SID Symposium Digest of Technical Papers > 55 > S1 > 1487 - 1490

With the growing demand for high‐quality Organic Light Emitting Diode (OLED) display, the design of screen structure by panel manufacturers needs to consider optical performance optimization carefully, such as Wide Angle Difference (WAD). The users hope that visual color bias of the OLED display on different angles appears as small as possible, and no red visual test will be particularly accepted...

article

Narirutin exerts anti‐inflammatory activity by inhibiting NLRP3 inflammasome activation in macrophages

Myong Hak Ri, Ming Yue Li, Yue Xing, Hong Xiang Zuo, more

Phytotherapy Research > 37 > 4 > 1293 - 1308

Citrus peel has long been used in traditional medicine in Asia to treat common cold, dyspepsia, cough, and phlegm. Narirutin–a flavanone‐7‐O‐glycoside–is the major flavonoid in citrus peel, and has anti‐oxidative, anti‐allergic, and anti‐inflammatory activities. However, the anti‐inflammatory mechanism of narirutin has not been fully elucidated. This study is aimed to investigate the effects of narirutin...

article

Convallatoxin inhibits IL‐1β production by suppressing zinc finger protein 91 (ZFP91)‐mediated pro‐IL‐1β ubiquitination and caspase‐8 inflammasome activity

Yue Xing, Jing Ying Wang, Ming Yue Li, Zhi Hong Zhang, more

British Journal of Pharmacology > 179 > 9 > 1887 - 1907

Background and Purpose ZFP91 positively regulates IL‐1β production in macrophages and may be a potential therapeutic target to treat inflammatory‐related diseases. We investigated whether this process is modulated by convallatoxin, which is a cardiac glycoside isolated from the traditional Chinese medicinal plant Adonis amurensis Regel et Radde. Experimental Approach In vitro, the mechanisms by...

article

Usnic acid suppresses cervical cancer cell proliferation by inhibiting PD‐L1 expression and enhancing T‐lymphocyte tumor‐killing activity

Tong Xin Sun, Ming Yue Li, Zhi Hong Zhang, Jing Ying Wang, more

Phytotherapy Research > 35 > 7 > 3916 - 3935

The programmed cell death 1 (PD‐1)/programmed death ligand 1 (PD‐L1) pathway is abnormally expressed in cervical cancer cells. Moreover, PD‐1/PD‐L1 blockade reduces the apoptosis and exhaustion of T cells and inhibits the development of malignant tumors. Usnic acid is a dibenzofuran compound originating from Usnea diffracta Vain and has anti‐inflammatory, antifungal, and anticancer activities. However,...

article

Association between KIAA0319 SNPs and risk of dyslexia: a meta-analysis

Ke-Gao Deng, Hua Zhao, Peng-Xiang Zuo

Journal of Genetics > 2019 > 98 > 2 > 1-7

The aetiology of developmental dyslexia (DD) is complex; although candidate genes have been suggested, the molecular mechanism and risk factors remain unknown. The KIAA0319 gene is functionally related to neuronal migration and axon growth, and several studies have examined associations between KIAA0319 polymorphisms with DD, but the results remain inconsistent. The sample size affects the results...

article

Chelidonine inhibits TNF‐α‐induced inflammation by suppressing the NF‐κB pathways in HCT116 cells

Zhi Hong Zhang, Chunliu Mi, Ke Si Wang, Zhe Wang, more

Phytotherapy Research > 32 > 1 > 65 - 75

Nuclear factor kappa‐light‐chain‐enhancer of activated B cells (NF‐κB) is a complex that regulates several hundreds of genes, including those involved in immunity and inflammation, survival, proliferation, and the negative feedback of NF‐κB signaling. Chelidonine, a major bioactive, isoquinoline alkaloid ingredient in Chelidonium majus, exhibits antiinflammatory pharmacological properties. However,...

article

Shikonin suppresses proliferation and induces cell cycle arrest through the inhibition of hypoxia-inducible factor-1α signaling

Ming Yue Li, Chunliu Mi, Ke Si Wang, Zhe Wang, more

Chemico-Biological Interactions > 2017 > 274 > C > 58-67

Hypoxia enhances the development of solid tumors. Hypoxia-inducible factor-1α (HIF-1α) is a transcription factor that is dominantly expressed under hypoxia in solid tumor cells and is a key factor of tumor regulation. HIF-1α regulates several target genes involved in many aspects of cancer progression, including angiogenesis, metastasis, and cell proliferation, as well as imparting resistance to cancer...

article

Imperatorin suppresses proliferation and angiogenesis of human colon cancer cell by targeting HIF-1α via the mTOR/p70S6K/4E-BP1 and MAPK pathways

Chunliu Mi, Juan Ma, Ke Si Wang, Hong Xiang Zuo, more

Journal of Ethnopharmacology > 2017 > 203 > C > 27-38

Angelica dahurica is a commonly used traditional Chinese medicine to treat migraine headache, toothache and cancer. Imperatorin is an active natural furocoumarin component originating from Angelica dahurica and has been shown to exhibit multiple bioeffector functions, including anti-cancer activity. However, the mechanism by which imperatorin inhibits tumor growth is not fully understood.The aim of...

article

The cortical surface correlates of clinical manifestations in the mid-stage sporadic Parkinson’s disease

Xia Deng, Fang-Jun Li, Chun-Yan Tang, Jie Zhang, more

Neuroscience Letters > 2016 > 633 > C > 125-133

The alteration of pathological cortical surface may lead to the corresponding clinical manifestations of sporadic Parkinson’s disease (sPD). Therefore, we investigated the correlates of cortical surface and clinical manifestations in the mid-stage sPD. Sixty seven mid-stage sPD patients and thirty five matched controls were performed the corticometry of magnetic resonance imaging (MRI) and the assessment...

article

The cortical thickness correlates of clinical manifestations in the mid-stage sporadic Parkinson’s disease

Xia Deng, Chun-Yan Tang, Jie Zhang, Lei Zhu, more

Neuroscience Letters > 2016 > 633 > C > 279-289

The cortical thickness has gained an extensive attention as a pathological alteration of sporadic Parkinson’s disease (sPD), the alteration of pathological cortical thickness may distinctly contribute to the consistent clinical manifestations. Therefore, we investigated the cortical thickness correlates of clinical manifestations in the mid-stage sPD from the Han population of Chinese mainland (HPCM)...

article

Synthesis and evaluation of (S)-[18F]fesetron in the rat brain as a potential PET imaging agent for serotonin 5-HT3 receptors

Neema K. Pithia, Christopher Liang, Xiang-Zuo Pan, Min-Liang Pan, more

Bioorganic & Medicinal Chemistry Letters > 2016 > 26 > 8 > 1919-1924

Serotonin 5-HT₃ receptors are involved in various brain functions including as an emesis target during cancer chemotherapy. We report here the development of (S)-2,3-dimethoxy-5-(3′-[¹⁸F]fluoropropyl)-N-(1-azabicyclo[2.2.2]oct-3-yl)benzamide ([¹⁸F]fesetron) as a potential PET imaging agent for serotonin 5-HT₃ receptors. By radiolabeling((S)-2,3-dimethoxy-5-(3′-tosyloxypropyl)-N-(1-azabicyclo[2.2.2]oct-3-yl)benzamide)...

article

The power of indirect ties

Xiang Zuo, Jeremy Blackburn, Nicolas Kourtellis, John Skvoretz, more

Computer Communications > 2016 > 73 > PB > 188-199

While direct social ties have been intensely studied in the context of computer-mediated social networks, indirect ties (e.g., friends of friends) have seen little attention. Yet in real life, we often rely on friends of our friends for recommendations (of good doctors, good schools, or good babysitters), for introduction to a new job opportunity, and for many other occasional needs. In this work...

article

Generating GPS satellite fractional cycle bias for ambiguity-fixed precise point positioning

Pan Li, Xiaohong Zhang, Xiaodong Ren, Xiang Zuo, more

GPS Solutions > 2016 > 20 > 4 > 771-782

With the development of precise point positioning (PPP), the School of Geodesy and Geomatics (SGG) at Wuhan University is now routinely producing GPS satellite fractional cycle bias (FCB) products with open access for worldwide PPP users to conduct ambiguity-fixed PPP solution. We provide a brief theoretical background of PPP and present the strategies and models to compute the FCB products. The practical...

chapter

The power of indirect ties in friend-to-friend storage systems

Xiang Zuo Jeremy Blackburn, Nicolas Kourtellis, John Skvoretz, Adriana Iamnitchi

14-th IEEE International Conference on Peer-to-Peer Computing > 1 - 5

2014 IEEE Thirteenth International Conference on Peer-to-Peer Computing (P2P)

Friend-to-Friend (F2F) storage systems were shown to suffer from two significant limitations. First, users with a small set of friends are penalized by lack of available storage for their needs, while users with many friends get overloaded with resource requests. Second, friends are typically in close geographical proximity to each other, and thus their online times are synchronized, leading to low...

article

Cytotoxic triterpenoids from Saussurea phyllocephala

Jiang Hu, Yan Song, Benshou Yang, Xiang Zuo, more

Archives of Pharmacal Research > 2014 > 37 > 12 > 1515-1521

Three new triterpenoids, 11α-hydroxy-lup-20(29)-ene-3β-palmitate (1), 28-hydroxy-20-oxo-30-norlupane-3β-palmitate (2), and 1β,11α,28-tyrihydroxy oleana-9(11),12-dien-3β-palmitate (3), together with three known compounds were isolated from the 95 % EtOH extract of Saussurea phyllocephala. The structures of the new compounds were elucidated on the basis of 1D and 2D NMR (COSY, HMQC, HMBC and NOESY)...

article

Enhanced performance of a novel gel polymer electrolyte by dual plasticizers

Xiang Zuo, Xiao-Min Liu, Feng Cai, Hui Yang, more

Journal of Power Sources > 2013 > 239 > Complete > 111-121

In this contribution, polyethylene glycol dilaurate (PEGDL) is synthesized and adopted as the physical cross-linking agent to enhance the performance, especially the mechanical property of the gel polymer electrolytes (GPEs). With polyethylene glycol dimethyl ether (PEGDME) as the main plasticizer and PEGDL as the secondary plasticizer, several gel polymer electrolytes based on a copolymer of methoxy-poly(ethylene...

article

The study of novel gel polymer electrolytes plasticized with non-volatile tris(methoxypolyethyleneglycol) aluminate esters

Feng Cai, Xiang Zuo, Xiao-Min Liu, Long Wang, more

Electrochimica Acta > 2013 > 106 > Complete > 209-214

A series of novel gel polymer electrolytes (GPEs) based on a co-polymer matrix of methoxy-poly(ethylene glycol) methacrylate (MPEGM) and hexadecal-poly(ethylene glycol) methacrylate (HPEGM) are synthesized in this study using non-volatile tris(methoxypolyethyleneglycol) aluminate ester ((MPEG _n ) ₃ -Al) as the plasticizer. Their thermal stability and ionic conductivity are studied...

article

Modeling of hysteretic behavior of the levitation force between superconductor and permanent magnet

Xing-da Wu, Ke-Xi Xu, Yue Cao, Shun-bo Hu, more

Physica C: Superconductivity and its applications > 2013 > 486 > Complete > 17-22

The hysteretic behavior of the levitation force between a permanent magnet and a melt-textured-growth YBCO bulk has been investigated under both zero-field cooling (ZFC) and field cooling (FC) processes. It is found that both in ZFC and FC measurements, the hysteresis loop for the first descent/ascent cycle of magnet is relatively larger than that for the second or third cycle, and the hysteresis...

article

Correcting phoneme recognition errors in learning word pronunciation through speech interaction

Xiang Zuo, Taisuke Sumii, Naoto Iwahashi, Mikio Nakano, more

Speech Communication > 2013 > 55 > 1 > 190-203

This paper presents a method called Interactive Phoneme Update (IPU) that enables users to teach systems the pronunciation (phoneme sequences) of words in the course of speech interaction. Using the method, users can correct mis-recognized phoneme sequences by repeatedly making correction utterances according to the system responses. The originalities of this method are: (1) word-segment-based correction...

chapter

Connecting People at a Conference: A Study of Influence between Offline and Online Using a Mobile Social Application

Xiang Zuo, Alvin Chin, Xiaoguang Fan, Bin Xu, more

2012 IEEE International Conference on Green Computing and Communications > 277 - 284

2012 IEEE International Conference on Green Computing and Communications (GreenCom)

Location-based mobile applications such as Foursquare and Jiepang help bridge the gap between offline and online. People that we encounter and connect with around physical resources such as conferences, provide opportunities for extending our social networks from offline to online. We give a preliminary study on the relationship between the online and physical social networks in terms of the online...

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INFONA - science communication portal

Search results for: Xiang Zuo

P‐15.20: Influence of OLED Touch Metal Mesh on Optical Performance

Narirutin exerts anti‐inflammatory activity by inhibiting NLRP3 inflammasome activation in macrophages

Convallatoxin inhibits IL‐1β production by suppressing zinc finger protein 91 (ZFP91)‐mediated pro‐IL‐1β ubiquitination and caspase‐8 inflammasome activity

Usnic acid suppresses cervical cancer cell proliferation by inhibiting PD‐L1 expression and enhancing T‐lymphocyte tumor‐killing activity

Association between KIAA0319 SNPs and risk of dyslexia: a meta-analysis

Chelidonine inhibits TNF‐α‐induced inflammation by suppressing the NF‐κB pathways in HCT116 cells

Shikonin suppresses proliferation and induces cell cycle arrest through the inhibition of hypoxia-inducible factor-1α signaling

Imperatorin suppresses proliferation and angiogenesis of human colon cancer cell by targeting HIF-1α via the mTOR/p70S6K/4E-BP1 and MAPK pathways

The cortical surface correlates of clinical manifestations in the mid-stage sporadic Parkinson’s disease

The cortical thickness correlates of clinical manifestations in the mid-stage sporadic Parkinson’s disease

Synthesis and evaluation of (S)-[18F]fesetron in the rat brain as a potential PET imaging agent for serotonin 5-HT3 receptors

The power of indirect ties

Generating GPS satellite fractional cycle bias for ambiguity-fixed precise point positioning

The power of indirect ties in friend-to-friend storage systems

Cytotoxic triterpenoids from Saussurea phyllocephala

Enhanced performance of a novel gel polymer electrolyte by dual plasticizers

The study of novel gel polymer electrolytes plasticized with non-volatile tris(methoxypolyethyleneglycol) aluminate esters

Modeling of hysteretic behavior of the levitation force between superconductor and permanent magnet

Correcting phoneme recognition errors in learning word pronunciation through speech interaction

Connecting People at a Conference: A Study of Influence between Offline and Online Using a Mobile Social Application

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