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Nobiletin, a citrus polymethoxylated flavone, exhibits multiple biological properties including anti-inflammatory, anti-carcinogenic, and anti-insulin resistance effects. The present study found that nobiletin exerted significant stimulatory effects on the contractility of isolated rat jejunal segments in all 6 different low contractile states, and meanwhile significant inhibitory effects in all 6...
ObjectivesThe aim of the study was to evaluate berberine‐induced bidirectional regulation on the contractility of jejunum.
MethodsDifferent low and high contractile states of isolated jejunal segment from rat were established to investigate the effects of berberine.
Key findingsStimulatory effects on jejunal segment were exerted by berberine in six low contractile states and inhibitory effects were...
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