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Brain‐penetrant neurotensin NTS1 receptor agonists produce antipsychotic drug‐like effects in animal models, including inhibition of conditioned avoidance responding and reversal of psychostimulant‐induced hyperactivity and stereotypy. Allosteric interactions between NTS1 receptors and dopamine D2 receptors may account for some of these antipsychotic effects. In order to determine the role that dopamine...
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