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The task of reliable recognition of promoters in eukaryotic genomes has not been yet solved completely. This is largely due to poor understanding of the features of the structure-function organization of eukaryotic promoters essential for their function and recognition. Five groups of promoters of tissue-specific genes were analyzed and vocabularies of region-specific oligonucleotide motifs were constructed...
A method is proposed to automatically search for patterns in the mutual location of context signals in regulatory DNA sequences. The procedure is based on the methods of Data Mining and Knowledge Discovery software, implemented in a computer system Gene Discovery. This system was used to study erythroid-specific promoters and promoters of the endocrine-system genes from TRRD. We detected some trends...
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