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• Ih is a hyperpolarisation‐activated current that influences neuronal excitability and is present in some sensory neurons.
• The magnitude and properties of Ih in different groups of sensory neurons that respond to painful stimuli (nociceptors) or to non‐painful stimuli, such as low threshold mechanoreceptors (LTMs), were unknown.
• We found that neurons with the greatest Ih were the nociceptors...
Muscle spindle afferent (MSA) neurons can show rapid and sustained firing. Immunostaining for the α3 isoform of the Na+/K+‐ATPase (α3) in some large dorsal root ganglion (DRG) neurons and large intrafusal fibres suggested α3 expression in MSAs (Dobretsov et al. 2003), but not whether α3‐immunoreactive DRG neuronal somata were exclusively MSAs. We found that neuronal somata with high α3 immunointensity...
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