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The cDNA for goose interferon gamma (goIFN-γ) was cloned from PHA-stimulated goose peripheral blood mononuclear cells (PBMCs) by RT-PCR. This cDNA encodes a 19-amino acid signal peptide and a 145-amino acid mature protein, which shares a high homology with duck IFN-γ. Recombinant mature goose interferon gamma (rgoIFN-γ) generated from both prokaryotic and eukaryotic expression systems effectively...
The cDNA of goose interferon-α (goIFN-α) was amplified from PHA stimulated PBMCs of goose by RT-PCR. The cDNA encodes a 30-amino acid signal peptide and a 161-amino acid mature protein, respectively. Recombinant mature goIFN-α (rgoIFN-α) expressed by prokaryotic and eukaryotic system possessed antiviral activity that was neutralized by rabbit anti-rgoIFN-α antibody in vitro. On the other hand, rgoIFN-α...
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