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The 5′ regulatory region of the mouse angiopoietin-like protein 4 (mANGPTL4), a remarkably versatile secreted protein responsible for hyperlipidaemia and angiogenesis, was cloned and functionally characterized. Three potential transcriptional start sites were determined by 5′-RACE and found to be at –129, –126 and –118, relative to the translation initiation codon. The activities of the putative promoters...
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