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Photoacoustic imaging has evolved as a promising deep‐tissue optical imaging modality. On page 5633, Y. Zhao and co‐workers demonstrate the inclusion complex of NaYF4:Yb3+,Er3+ upconversion nanoparticles with α‐cyclodextrin in aqueous conditions that exhibits luminescence quenching when excited at 980 nm. This non‐radiative relaxation leads to photoacoustic signal enhancement in vivo, showing high...
An inclusion complex of NaYF4:Yb3+,Er3+ upconversion nanoparticles with α‐cyclodextrin in aqueous conditions exhibits luminescence quenching when excited at 980 nm. This non‐radiative relaxation leads to an unprecedented photoacoustic signal enhancement. In vivo localization of α‐cyclodextrin‐covered NaYF4:Yb3+,Er3+ is demonstrated using photoacoustic tomography in live mice, showing its high capability...
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