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Focused ultrasound thermal therapy relies on temperature monitoring for treatment guidance and assurance of targeting and dose control; a potential approach to achieve these is ultrasonic temperature estimation. The approach used currently involves the detection of echo time shifts based on cross-correlation processing from the segmented radio-frequency (RF) data. In this study, we propose a novel...
The purpose of this paper is to demonstrate a prototype design of a low-frequency multiple-channel hemispherical focused-ultrasound phased-array system for transcranial disruption of the blood-brain barrier (BBB). A 32-channel ultrasound driving system tunable in the frequency range from 200 to 400 kHz was designed for producing a suitable ultrasound output for BBB disruption. The driving system includes...
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