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The fate of stem cells at the single cell level with limited communication with other cells is still unknown due to the lack of an efficient tool for highly accurate molecular detection. Moreover, the conditional sensitivity of biological experiments requires a sufficient number of parallel experiments to support a conclusion. In this work, a microfluidic single cell chip is designed for use with...
In article number 1905001, Lin Han, Hong Liu, Yuanhua Sang, and co‐workers design a microfluidic single cell chip with a protein chip to study the effect of hydroxyapatite (HAp) on the osteogenic differentiation of human adiposederived stem cells (hADSCs) in situ at the single cell level. The detection of secretory proteins confirms that HAp nanorods enhance osteogenic differentiation at the single...
Ever‐growing tissue regeneration and other stem cell therapies cause pressing need for large population of self‐renewable stem cells. However, stem cells gradually lose their stemness after long‐term in vitro cultivation. In this study, a ZnO nanorod (ZnO NR) array is used to maintain the stemness of human adipose‐derived stem cells (hADSCs). The results prove that after culturing hADSCs on ZnO NRs...
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