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Simulated Moving Bed chromatography has become a widely used separation technology in die pharmaceutical and fine chemical industries. In particular, the separation of enantimeric mixtures has received recently great interest because it can achieve good performances and high productions. SMB process is a typical hybrid system with both continuous and discrete variables. The thesis proposed the SMB...
Based on the single column partial differential equation model for the industry chromatographic separation, the mathematical model of the Simulated Moving Bed chromatographic separation process is established from the flow and mass conservation relations of the SMB process. Method of line is used for the numeric model computations. Computerized simulation results show that compared with the true moving...
Chromatographic process provides a powerful tool for the separation of multicomponent mixtures. In recent years, simulated moving bed (SMB) technology has become increasingly attractive for complex separation tasks and emerged as the leading chromatographic separation technique in the fields of pharmaceuticals, fine chemicals, and biotechnology. In this paper, a detailed model that takes into account...
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