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Cytate, a receptor-targeted contrast agent and independent component analysis (ICA) was used to enhance the contrast between a pair of stained small pieces of cancerous and normal prostate tissues embedded in large piece normal tissue.
Accurate diagnosis and treatment of various pathologic conditions can be achieved by integrating multimodal imaging systems that furnish complementary information to improve patient management. The availability of high-resolution tomography systems, fast computers, and image reconstruction algorithms has improved disease diagnosis and treatment management. As medical practice moves into the molecular...
Optical approaches to small animal in vivo molecular imaging provide high sensitivity, stable non-radioactive probes, and an extensive array of functional reporting strategies. However, quantitative whole body assays remain illusive. The quantitative accuracy of optical imaging is affected by the depth of the buried target and the heterogeneity of tissue optical properties. Tomography approaches,...
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