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We evaluated the expression and function of the microglia‐specific growth factor, Progranulin‐a (Pgrn‐a) during developmental neurogenesis in the embryonic retina of zebrafish. At 24 hpf pgrn‐a is expressed throughout the forebrain, but by 48 hpf pgrn‐a is exclusively expressed by microglia and/or microglial precursors within the brain and retina. Knockdown of Pgrn‐a does not alter the onset of neurogenic...
Cover: The cover, by Caroline E. Walsh and Peter F. Hitchcock, is based on the Research Article Progranulin regulates neurogenesis in the developing vertebrate retina, DOI: 10.1002/dneu.22499.
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