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Recent studies show helium may be one kind of neuroprotective gas. This study aimed to examine the short and long-term neuroprotective effects of helium preconditioning in an established neonatal cerebral hypoxia–ischemia (HI) model. Seven-day-old rat pups were subjected to left common carotid artery ligation and then 90min of hypoxia (8% oxygen at 37°C). The preconditioning group inhaled 70% helium–30%...
Cerebral hypoxia–ischemia (HI) represents a major cause of brain damage in the term newborn. This study aimed to examine the short and long-term neuroprotective effect of hydrogen saline (H 2 saline) using an established neonatal HI rat pup model. Seven-day-old rat pups were subjected to left common carotid artery ligation and then 90 min hypoxia (8% oxygen at 37 °C). H 2 saturated...
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