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(2R)-(3-Amino-2-fluoropropyl)sulphinic acid (AFPSiA) is a potent GABA B agonist, which makes it a possible alternative in future GERD treatment. The degradation of AFPSiA was investigated to support the drug-development effort. The compound is too polar to be compatible with regular reversed-phase LC. Moreover, the compound and the degradation products cannot be detected by UV due to low absorption...
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