Search results for: Zhang Yuan

Items from 1 to 20 out of 242 results

article

Frontispiz: An Organophosphorescence Probe with Ultralong Lifetime and Intrinsic Tissue Selectivity for Specific Tumor Imaging and Guided Tumor Surgery

Heqi Gao, Tingting Zhang, Yunxiang Lei, Di Jiao, more

Angewandte Chemie > 136 > 42 > n/a - n/a

Bioimaging. In their Research Article (e202406651), Yunxiang Lei, Qiao Jin, Dan Ding et al. systematically demonstrate that phosphorescence lifetime is the most crucial factor in enhancing the imaging quality of room‐temperature phosphorescence materials for bioimaging.

article

An Organophosphorescence Probe with Ultralong Lifetime and Intrinsic Tissue Selectivity for Specific Tumor Imaging and Guided Tumor Surgery

Heqi Gao, Tingting Zhang, Yunxiang Lei, Di Jiao, more

Angewandte Chemie > 136 > 42 > n/a - n/a

Organic phosphorescent materials are excellent candidates for use in tumor imaging. However, a systematic comparison of the effects of the intensity, lifetime, and wavelength of phosphorescent emissions on bioimaging performance has not yet been undertaken. In addition, there have been few reports on organic phosphorescent materials that specifically distinguish tumors from normal tissues. This study...

article

Frontispiece: An Organophosphorescence Probe with Ultralong Lifetime and Intrinsic Tissue Selectivity for Specific Tumor Imaging and Guided Tumor Surgery

Heqi Gao, Tingting Zhang, Yunxiang Lei, Di Jiao, more

Angewandte Chemie International Edition > 63 > 42 > n/a - n/a

article

An Organophosphorescence Probe with Ultralong Lifetime and Intrinsic Tissue Selectivity for Specific Tumor Imaging and Guided Tumor Surgery

Heqi Gao, Tingting Zhang, Yunxiang Lei, Di Jiao, more

Angewandte Chemie International Edition > 63 > 42 > n/a - n/a

article

P450‐Modified Multicyclic Cyclophane‐Containing Ribosomally Synthesized and Post‐Translationally Modified Peptides

Cheng Li Liu, Zi Jie Wang, Jing Shi, Zhang Yuan Yan, more

Angewandte Chemie International Edition > 63 > 10 > n/a - n/a

Cyclic peptides with cyclophane linkers are an attractive compound type owing to the fine‐tuned rigid three‐dimensional structures and unusual biophysical features. Cytochrome P450 enzymes are capable of catalyzing not only the C−C and C−O oxidative coupling reactions found in vancomycin and other nonribosomal peptides (NRPs), but they also exhibit novel catalytic activities to generate cyclic ribosomally...

article

P450‐Modified Multicyclic Cyclophane‐Containing Ribosomally Synthesized and Post‐Translationally Modified Peptides

Cheng Li Liu, Zi Jie Wang, Jing Shi, Zhang Yuan Yan, more

Angewandte Chemie > 136 > 10 > n/a - n/a

article

Detachable MOF‐Based Core/Shell Nanoreactor for Cancer Dual‐Starvation Therapy With Reversing Glucose and Glutamine Metabolisms

Huiping Du, Siyu Meng, Meijuan Geng, Pan Zhao, more

Small > 19 > 42 > n/a - n/a

Tumor‐dependent glucose and glutamine metabolisms are essential for maintaining survival, while the accordingly metabolic suppressive therapy is limited by the compensatory metabolism and inefficient delivery efficiency. Herein, a functional metal–organic framework (MOF)‐based nanosystem composed of the weakly acidic tumor microenvironment‐activated detachable shell and reactive oxygen species (ROS)‐responsive...

article

Biosynthesis of Sordarin Revealing a Diels–Alderase for the Formation of the Norbornene Skeleton

Shuang He Liu, Jia Li Sun, Yi Ling Hu, Li Zhang, more

Angewandte Chemie > 134 > 33 > n/a - n/a

Sordarin (1) is a fungal diterpene glycoside that displays potent antifungal bioactivity through inhibition of elongation factor 2. The structures of sordarin and related compounds feature a highly rearranged tetracyclic diterpene core. In this study, we identified a concise pathway in the biosynthesis of sordarin. A diterpene cyclase (SdnA) generates the 5/8/5 cycloaraneosene framework, which is...

article

Biosynthesis of Sordarin Revealing a Diels–Alderase for the Formation of the Norbornene Skeleton

Shuang He Liu, Jia Li Sun, Yi Ling Hu, Li Zhang, more

Angewandte Chemie International Edition > 61 > 33 > n/a - n/a

article

Accessing Excitation‐ and Time‐Responsive Afterglows from Aqueous Processable Amorphous Polymer Films through Doping and Energy Transfer

Zhengshuo Wang, Anze Li, Zihao Zhao, Tianwen Zhu, more

Advanced Materials > 34 > 31 > n/a - n/a

Smart afterglow materials in response to excitation and delay time, including crystals, polymeric films, and carbon dots, have attracted considerable attention on account of their fundamental value in photophysics and promising applications in optoelectronics. However, the fabrication of amorphous and flexible polymer films with fine control remains underexplored. Herein, new doped polymer films based...

article

Polydopamine‐Mediated Interfacial Functionalization of Implants for Accelerating Infected Bone Repair through Light‐Activatable Antibiosis and Carbon Monoxide Gas Regulated Macrophage Polarization

Zhang Yuan, Jianshuang Wu, Zhenxiang Fu, Siyu Meng, more

Advanced Functional Materials > 32 > 27 > n/a - n/a

Current treatments for implant‐associated infection remain unsatisfactory due to secondary infection and excessive inflammation, which impairs osseointegration. Herein, an interfacial functionalization strategy is proposed by the integration of a carbon monoxide gas (CO) nanogenerator on titanium implants, followed by covalently grafting arginine‐glycine‐aspartic acid (RGD) polypeptide. Under near‐infrared...

article

Unprecedented and Readily Tunable Photoluminescence from Aliphatic Quaternary Ammonium Salts**

Saixing Tang, Zihao Zhao, Jinquan Chen, Tianjia Yang, more

Angewandte Chemie International Edition > 61 > 16 > n/a - n/a

Compounds bearing aliphatic amines can be emissive under appropriate conditions. However, their ionized counterparts, namely, quaternary ammonium salts (QASs), which are widely used as phase‐transfer catalysts, ionic liquids, disinfectants, and surfactants, are known as luminescence quenchers and considered nonemissive. Herein, unprecedented intrinsic fluorescence/phosphorescence dual emissions from...

article

Unprecedented and Readily Tunable Photoluminescence from Aliphatic Quaternary Ammonium Salts**

Saixing Tang, Zihao Zhao, Jinquan Chen, Tianjia Yang, more

Angewandte Chemie > 134 > 16 > n/a - n/a

article

Calcium Peroxide Nanoparticles‐Embedded Coatings on Anti‐Inflammatory TiO₂ Nanotubes for Bacteria Elimination and Inflammatory Environment Amelioration

Ye He, Ke Li, Xin Yang, Jin Leng, more

Small > 17 > 47 > n/a - n/a

Implant‐associated bacterial infections significantly impair the integration between titanium and soft tissues. Traditional antibacterial modifications of titanium implants are able to eliminate bacteria, but the resulting pro‐inflammatory reactions are usually ignored, which still poses potential risks to human bodies. Here, a dual drug‐loading system on titanium has been developed via the adhesion...

article

Michael Polyaddition Approach Towards Sulfur Enriched Nonaromatic Polymers with Fluorescence‐Phosphorescence Dual Emission

Fahmeeda Kausar, Zihao Zhao, Tianjia Yang, Wubeiwen Hou, more

Macromolecular Rapid Communications > 42 > 11 > n/a - n/a

Nonaromatic photoluminescent polymers have attracted great attention due to their intriguing photophysical properties and promising implications in optoelectronic and biological areas. The luminescence from these nonconventional luminophores can be well rationalized by the clustering‐triggered emission mechanism. Sulfur, although as an n‐electron‐rich element with big radius, is not been widely utilized...

article

Near‐Infrared Light‐Activatable Dual‐Action Nanoparticle Combats the Established Biofilms of Methicillin‐Resistant Staphylococcus aureus and Its Accompanying Inflammation

Zhang Yuan, Chuanchuan Lin, Liangliang Dai, Ye He, more

Small > 17 > 13 > n/a - n/a

Clinically, inhibition of both bacterial infection and excessive inflammation is a crucial step for improved wound treatments. Herein, the fabrication of near‐infrared‐light (NIR)‐activatable deoxyribonuclease (DNase)–carbon monoxide (CO)@mesoporous polydopamine nanoparticles (MPDA NPs) is demonstrated for efficient elimination of methicillin‐resistant Staphylococcus aureus (MRSA) biofilms and the...

article

Effective Internal and External Modulation of Nontraditional Intrinsic Luminescence

Yueying Lai, Tianwen Zhu, Ting Geng, Shuyuan Zheng, more

Small > 16 > 49 > n/a - n/a

The rational modulation of the nontraditional intrinsic luminescence (NTIL) of nonconventional luminophores remains difficult, on account of the limited understanding on the structure–property relationships and emission mechanisms. Herein, the effective modulation of NTIL is demonstrated based on a group of nonaromatic anhydrides and imides. Mutual bridging of isolated subgroups effectively promotes...

article

Color‐Tunable, Excitation‐Dependent, and Time‐Dependent Afterglows from Pure Organic Amorphous Polymers

Xueyu Dou, Tianwen Zhu, Zhengshuo Wang, Wei Sun, more

Advanced Materials > 32 > 47 > n/a - n/a

Achieving persistent room‐temperature phosphorescence (p‐RTP), particularly those of tunable full‐colors, from pure organic amorphous polymers is attractive but challenging. Particularly, those with tunable multicolor p‐RTP in response to excitation wavelength and time are highly important but both fundamentally and technically underexplored. Here, a facile and general strategy toward color‐tunable...

article

Accessing Tunable Afterglows from Highly Twisted Nonaromatic Organic AIEgens via Effective Through‐Space Conjugation

Shuyuan Zheng, Tianwen Zhu, Yunzhong Wang, Tianjia Yang, more

Angewandte Chemie > 132 > 25 > 10104 - 10108

Nonaromatic, cross‐conjugated, and highly twisted luminogens consisting of acylated succinimides demonstrate aggregation‐induced emission characteristics along with tunable multicolor photoluminescence and afterglows in their single crystals. Effective through‐space conjugation among different moieties bearing n/π electrons promote the spin–orbit coupling and intersystem crossing and lead to diverse...

article

Accessing Tunable Afterglows from Highly Twisted Nonaromatic Organic AIEgens via Effective Through‐Space Conjugation

Shuyuan Zheng, Tianwen Zhu, Yunzhong Wang, Tianjia Yang, more

Angewandte Chemie International Edition > 59 > 25 > 10018 - 10022

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INFONA - science communication portal

Search results for: Zhang Yuan

Frontispiz: An Organophosphorescence Probe with Ultralong Lifetime and Intrinsic Tissue Selectivity for Specific Tumor Imaging and Guided Tumor Surgery

An Organophosphorescence Probe with Ultralong Lifetime and Intrinsic Tissue Selectivity for Specific Tumor Imaging and Guided Tumor Surgery

Frontispiece: An Organophosphorescence Probe with Ultralong Lifetime and Intrinsic Tissue Selectivity for Specific Tumor Imaging and Guided Tumor Surgery

An Organophosphorescence Probe with Ultralong Lifetime and Intrinsic Tissue Selectivity for Specific Tumor Imaging and Guided Tumor Surgery

P450‐Modified Multicyclic Cyclophane‐Containing Ribosomally Synthesized and Post‐Translationally Modified Peptides

P450‐Modified Multicyclic Cyclophane‐Containing Ribosomally Synthesized and Post‐Translationally Modified Peptides

Detachable MOF‐Based Core/Shell Nanoreactor for Cancer Dual‐Starvation Therapy With Reversing Glucose and Glutamine Metabolisms

Biosynthesis of Sordarin Revealing a Diels–Alderase for the Formation of the Norbornene Skeleton

Biosynthesis of Sordarin Revealing a Diels–Alderase for the Formation of the Norbornene Skeleton

Accessing Excitation‐ and Time‐Responsive Afterglows from Aqueous Processable Amorphous Polymer Films through Doping and Energy Transfer

Polydopamine‐Mediated Interfacial Functionalization of Implants for Accelerating Infected Bone Repair through Light‐Activatable Antibiosis and Carbon Monoxide Gas Regulated Macrophage Polarization

Unprecedented and Readily Tunable Photoluminescence from Aliphatic Quaternary Ammonium Salts**

Unprecedented and Readily Tunable Photoluminescence from Aliphatic Quaternary Ammonium Salts**

Calcium Peroxide Nanoparticles‐Embedded Coatings on Anti‐Inflammatory TiO₂ Nanotubes for Bacteria Elimination and Inflammatory Environment Amelioration

Michael Polyaddition Approach Towards Sulfur Enriched Nonaromatic Polymers with Fluorescence‐Phosphorescence Dual Emission

Near‐Infrared Light‐Activatable Dual‐Action Nanoparticle Combats the Established Biofilms of Methicillin‐Resistant Staphylococcus aureus and Its Accompanying Inflammation

Effective Internal and External Modulation of Nontraditional Intrinsic Luminescence

Color‐Tunable, Excitation‐Dependent, and Time‐Dependent Afterglows from Pure Organic Amorphous Polymers

Accessing Tunable Afterglows from Highly Twisted Nonaromatic Organic AIEgens via Effective Through‐Space Conjugation

Accessing Tunable Afterglows from Highly Twisted Nonaromatic Organic AIEgens via Effective Through‐Space Conjugation

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