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Medical imaging through a targeting agent promises to improve the specificity and sensitivity of cancer detection. Nanoparticles (NPs) may provide advantages for targeted photoacoustic (PA) imaging due to their unique physical and optical properties. In our previous study, we developed a phase-change contrast agent made from a biodegradable polymer, poly(lactic-co-glycolic acid) (PLGA) and loaded...
In this study, a phase-change contrast agent made of biodegradable polymer PLGA and loaded with gold nanorods (GNRs) and perfluorohexane were conjugated to an anti-HER2 antibody (Herceptin) for specific binding to breast cancer cells that overexpress HER2 receptors. The mean size of the nanoparticles (NPs) was about 500 nm. The targeting specificity of PLGA-GNR-Herceptin NPs was examined using fluorescent...
A series of 57Fe‐doped TiO2 and 57Fe/Sn‐codoped TiO2 materials were prepared by a soft‐chemical solution process with various 57Fe concentrations from 0.1 to 1.0 at.‐% and a fixed Sn concentration of 2.0 at.‐%. In this process, an aqueous H2O2 solution reacts with iron and titanium or iron, tin, and titanium precursor compounds to produce peroxopolymetallic acids. The structures and magnetic properties...
Optical sensors based on nanoparticles induced Localized Surface Plasmon Resonance are more sensitive to real-time chemical and biological sensing, which have attracted intensive attentions in many fields. In this paper, we establish a simulation model based on nanoparticles imprinted polymer to increase sensitivity of the LSPR sensor by detecting the changes of Surface Plasmon Resonance signals....
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