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Healthy adult joint cartilage contains neither blood vessels nor nerves. Osteoarthritic cartilage, in contrast, may be invaded by blood vessels from the subchondral bone. The mechanisms underlying cartilage angiogenesis in osteoarthritis are unclear but may involve hypertrophic chondrocyte differentiation. Active research is under way to identify the factors involved in cartilage angiogenesis. Here,...
Le cartilage articulaire adulte sain est un tissu dépourvu de vaisseaux sanguins et d’innervation. À l’inverse, le cartilage arthrosique est parfois envahi par des vaisseaux sanguins provenant de l’os sous-chondral. Les causes de cette néovascularisation ne sont pas encore clairement identifiées, mais semblent trouver leur origine dans la différenciation hypertrophique des chondrocytes. L’identification...
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