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Background
Castrate‐resistant prostate cancer (CRPC) is an aggressive and lethal disease. The pathogenesis of CRPC is not fully understood and novel therapeutic targets need to be identified to improve the patients' prognosis. MicroRNA‐30a (miR‐30a) has been demonstrated to be a tumor suppressor in many types of solid malignancies. However, its role in androgen‐independent (AI) growth of prostate...
BACKGROUNDMicroRNAs (miRNAs) are noncoding RNAs that are important for embryonic stem cell development and epithelial to mesenchymal transition (EMT). Accumulating evidence indicates that miRNAs play critical roles in prostate cancer (PCa) metastasis and have potential use as therapeutic targets. Although dysregulated miR‐132/212 have been suggested to be directly involved in the proliferation and...
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