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We demonstrate the establishment of a novel animal model for trigeminal neuropathic pain following compression of the trigeminal nerve root, which produces prolonged nociceptive behavior and demyelination of the trigeminal nerve root. Under anesthesia, male Sprague–Dawley rats (200–230g) were mounted onto a stereotaxic frame and injections of a 4% agar solution (10μl) were given to achieve compression...
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