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Methicillin-resistant staphylococcus aureus is an emerging problem for the treatment of chronic suppurative otitis media, and also for pediatric tympanostomy tube otorrhea. To date, there are no effective topical antibiotic drugs to treat methicillin-resistant staphylococcus aureus otorrhea.In this study, we evaluated the ototoxicity of topical KR-12-a2 solution on the cochlea when it is applied topically...
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