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Simultaneous kidney‐pancreas transplantation (SKP Tx) is a treatment for end‐stage kidney disease secondary to diabetes mellitus. We investigated the role of immune responses to donor human leukocyte antigens (HLA) and tissue‐restricted kidney and pancreas self‐antigens (KSAgs and PSAgs, respectively) in SKP Tx recipients (SKP TxRs). Sera collected from 39 SKP TxRs were used to determine de novo Abs...
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