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To evaluate various treatment modalities for vulvar intraepithelial neoplasia (VIN) in relation to possible risk factors for recurrence.Retrospective review of 93 patients with VIN treated by CO 2 laser vaporization, photodynamic therapy with aminolevulinic acid (PDT), excision or vulvectomy.40.4% of the 47 patients with laser vaporization, 48.1% of 27 patients with PDT, 42% of 12 patients...
Vulvar intraepithelial neoplasia (VIN) is a premalignant disease of the lower genital tract. The increased occurrence of high-risk human papillomavirus (HPV) infection seems to be associated with the increasing frequency of VIN. Integration of HPV DNA into host chromosome has been hypothesized to be a critical step in the carcinogenesis of cervical neoplasia resulting in altered expression of two...
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