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Background Drug repositioning is the process of identifying new targets for known drugs. It can be used to overcome problems associated with traditional drug discovery by adapting existing drugs to treat new discovered diseases. Thus, it may reduce associated risk, cost and time required to identify and verify new drugs. Nowadays, drug repositioning has received more attention from industry and academia...
It is becoming a common practice to use recommendation systems to serve users of web-based platforms such as social networking platforms, review web-sites, and e-commerce web-sites. Each platform produces recommendations by capturing, maintaining and analyzing data related to its users and their behavior. However, people generally use different web-based platforms for different purposes. Thus, each...
Gene regulatory networks (GRNs) are composed of biological components, including genes, proteins and metabolites, and their interactions. In general, computational methods are used to infer the connections among these components. However, computational methods should take into account the general features of the GRNs, which are sparseness, scale-free topology, modularity and structure of the inferred...
Web-based platforms, such as social networks, review web-sites, and e-commerce web-sites, commonly use recommendation systems to serve their users. The common practice is to have each platform captures and maintains data related to its own users. Later the data is analyzed to produce user specific recommendations. We argue that recommendations could be enriched by considering data consolidated from...
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