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Electroconvulsive therapy (ECT) is a highly effective treatment for severe depressive disorder. Efficacy and cognitive outcomes have been shown to depend on variations in electrode placement and other stimulus parameters, presumably because of differences in the pattern of neuronal activation. This latter effect, however, is poorly understood.In this study, we present an anatomically accurate human...
Electroconvulsive therapy (ECT) is the most effective treatment for severe depressive disorder, and yet the mechanisms of its therapeutic effects remain largely unknown. A novel computational model is presented in this study to simulate and investigate direct cortical excitation caused by bitemporal electroconvulsive therapy (BT ECT), using a finite element model (FEM) of the human head. The skull...
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