Search results for: Hideyuki Kinoshita

Items from 1 to 20 out of 32 results

article

Fluorescence in situ hybridization‐negative intra‐articular myxoid liposarcoma with complex rearrangements involving EWSR1::DDIT3 detected using nanopore sequencing

Naohiro Makise, Jason Lin, Hajime Kageyama, Naoki Takeda, more

Pathology International > 74 > 10 > 604 - 610

Myxoid liposarcoma (MLPS) is a rare sarcoma, typically arising in deep soft tissues during the fourth to fifth decades of life. Histologically, MLPS is composed of uniform oval cells within a background of myxoid stroma and chicken‐wire capillaries. Genetically, MLPS is characterized by the FUS/EWSR1::DDIT3 fusion gene, which generally results from balanced interchromosomal translocation and is detectable...

article

Nanopore DNA Sequencing Detected Chromothripsis‐Induced PAFAH1B1::USP6 Rearrangement in Periosteal Solid Aneurysmal Bone Cyst Initially Diagnosed as Osteosarcoma

Naohiro Makise, Jason Lin, Hajime Kageyama, Hideyuki Kinoshita, more

Genes, Chromosomes and Cancer > 63 > 7 > n/a - n/a

An aneurysmal bone cyst (ABC) is a benign bone neoplasm that typically occurs during the first and second decades of life. ABC usually presents as a rapidly growing intramedullary expansile mass with multiple blood‐filled cysts in the metaphysis of the long tubular bones. Here, we report a case of a periosteal solid ABC that was initially diagnosed as a high‐grade surface osteosarcoma. A 10‐year‐old...

article

Metastasizing aneurysmal dermatofibroma initially diagnosed as angiosarcoma confirmed by CD63::PRKCD fusion gene detection with nanopore sequencing

Naoki Takeda, Naohiro Makise, Jason Lin, Hajime Kageyama, more

Genes, Chromosomes and Cancer > 63 > 5 > n/a - n/a

Dermatofibroma (DF) is a benign tumor that forms pedunculated lesions ranging in size from a few millimeters to 2 cm, usually affecting the extremities and trunks of young adults. Histopathologically, DF is characterized by the storiform proliferation of monomorphic fibroblast‐like spindle cells. In addition to neoplastic cells, secondary elements such as foamy histiocytes, Touton‐type giant cells,...

article

Analysis of implants for metastatic bone tumors of the proximal femur: A retrospective study

Fumihide Terakawa, Hiroto Kamoda, Tsukasa Yonemoto, Yoko Hagiwara, more

Asia‐Pacific Journal of Clinical Oncology > 19 > 5 > e320 - e325

Aim To investigate the relationship between surgical techniques used in our hospital to treat metastatic bone tumors of the proximal femur and activity level and prognosis of patients and whether the location of the tumor is considered when selecting surgical techniques. Methods We retrospectively reviewed 82 patients with metastatic bone tumors of the proximal femur who underwent intramedullary...

article

Relationship between patient-based scoring systems and the activity level of patients measured by wearable activity trackers in lumbar spine disease

Masahiro Inoue, Sumihisa Orita, Kazuhide Inage, Miyako Suzuki, more

European Spine Journal > 2019 > 28 > 8 > 1804-1810

Purposes To evaluate whether a relationship exists between patient-based scoring systems and the activity level of patients with low back pain (LBP) by using wearable activity trackers, and to determine whether activity level was affected by patient factors. Methods The subjects were 66 patients with LBP. The physical activity of participants was objectively evaluated using the Micro-Motion logger...

article

Successful total en bloc spondylectomy of the L3 vertebra with a paravertebral giant cell tumor following preoperative treatment with denosumab: a case report

Hideyuki Kinoshita, Sumihisa Orita, Tsukasa Yonemoto, Takeshi Ishii, more

Journal of Medical Case Reports > 2019 > 13 > 1 > 1-5

Background Giant cell tumor is known to be a benign neoplasm that arises most commonly in the long bones, while cases in the spine are rare. Recently, denosumab, a monoclonal antibody that inhibits receptor activator of nuclear factor-kappa β ligand, has been used to treat patients with giant cell tumor. However, there are few reports of total en bloc spondylectomy being used for paravertebral giant...

article

Macro-pro-B-type natriuretic peptide (proBNP) and hidden macro-N-terminal proBNP: Case report

Yasuaki Nakagawa, Toshio Nishikimi, Hiroshi Sakai, Seiko Ohno, more

Clinical Biochemistry > 2018 > 52 > C > 148-152

B-type natriuretic peptide (BNP) is a cardiac hormone widely used as a biomarker for heart failure. Here, we present the first report of extremely high levels of immunoreactive BNP caused by formation of macro-proBNP.A 70-year-old woman with left ventricular hypertrophy and normal systolic function presented with extremely high plasma levels of BNP (35,374pg/ml) and N-terminal proBNP (NT-proBNP; 30,600pg/ml)...

article

Acute Effects of Inhaled Iloprost in Pulmonary Arterial Hypertension Patients with Lung Disease

Munekazu Tanaka, Hideyuki Kinoshita, Hiromu Yanagisawa, Kenji Moriuchi, more

Journal of Cardiac Failure > 2017 > 23 > 10(S) > S65-S66

article

Clinical Features of the Systemic Sclerosis Associated Pulmonary Arterial Hypertension with Left Heart Disease

Hiromu Yanagisawa, Hideyuki Kinoshita, Kouichirou Kuwahara, Hajime Yoshifuji, more

Journal of Cardiac Failure > 2017 > 23 > 10(S) > S65

article

A Case of Macro-pro-B-Type Natriuretic Peptide (proBNP)

Yasuaki Nakagawa, Toshio Nishikimi, Hiroshi Sakai, Seiko Ohno, more

Journal of Cardiac Failure > 2017 > 23 > 10(S) > S62

article

Outcomes of various transplant procedures (single, sparing, inverted) in living-donor lobar lung transplantation

Hiroshi Date, Akihiro Aoyama, Kyoko Hijiya, Hideki Motoyama, more

The Journal of Thoracic and Cardiovascular Surgery > 2017 > 153 > 2 > 479-486

In standard living-donor lobar lung transplantation (LDLLT), the right and left lower lobes from 2 healthy donors are implanted. Because of the difficulty encountered in finding 2 donors with ideal size matching, various transplant procedures have been developed in our institution. The purpose of this retrospective study was to compare outcomes of nonstandard LDLLT with standard LDLLT.Between June...

article

Characteristic of Diagnostic Modalities and Corticosteroid Therapy in Cardiac Sarcoidosis

Hiromu Yanagisawa, Hideyuki Kinoshita, Takao Katou, Naritatsu Saitou, more

Journal of Cardiac Failure > 2016 > 22 > 9(S) > S167

article

Surgical treatment for far-out syndrome associated with abnormal fusion of the L5 vertebral corpus and L4 hemivertebra: a case report

Shohei Ise, Koki Abe, Sumihisa Orita, Tetsuhiro Ishikawa, more

BMC Research Notes > 2016 > 9 > 1 > 1-6

Background Far-out syndrome was reported by Wiltse et al. in 1984, which is a condition characterized by L5 spinal nerve radiculopathy due to nerve compression between the L5 transverse process and sacral alar. Although many cases of far-out syndrome have been reported, to our knowledge, the present case firstly showed far-out syndrome due to assimilated L4 hemivertebra and L5 vertebra through which...

article

Role of O-glycosylation in N-terminal Region of Human proBNP in proBNP Processing

Yasuaki Nakagawa, Toshio Nishikimi, Koichiro Kuwahara, Shinji Yasuno, more

Journal of Cardiac Failure > 2014 > 20 > 10 Supplement > S151

article

Pivotal Involvement of Renin-angiotensin System in Generating Arrhythmogenic Substrates in Mice with Chronic Heart Failure and Lethal Arrhythmias

Chinatsu Yamada, Koichiro Kuwahara, Hideyuki Kinoshita, Yasuaki Nakagawa, more

Journal of Cardiac Failure > 2014 > 20 > 10 Supplement > S185

article

Blockade of TRPC6 is a novel therapeutic approach against pathological cardiac remodeling

Hideyuki Kinoshita, Koichiro Kuwahara, Motohiro Nishida, Hitoshi Kurose, more

Life Sciences > 2013 > 93 > 25-26 > e63

article

Evaluation of proBNP in End-stage Renal Disease Patients on Hemodialysis

Yasuaki Nakagawa, Toshio Nishikimi, Koichiro Kuwahara, Shinji Yasuno, more

Journal of Cardiac Failure > 2013 > 19 > 10 Supplement > S168

article

Two Susceptibility Loci to Takayasu Arteritis Reveal a Synergistic Role of the IL12B and HLA-B Regions in a Japanese Population

Chikashi Terao, Hajime Yoshifuji, Akinori Kimura, Takayoshi Matsumura, more

The American Journal of Human Genetics > 2013 > 93 > 2 > 289-297

Takayasu arteritis (TAK) is an autoimmune systemic vasculitis of unknown etiology. Although previous studies have revealed that HLA-B ^∗ 52:01 has an effect on TAK susceptibility, no other genetic determinants have been established so far. Here, we performed genome scanning of 167 TAK cases and 663 healthy controls via Illumina Infinium Human Exome BeadChip arrays, followed by a replication...

article

Angiotensin II‐induced cardiac hypertrophy and fibrosis are promoted in mice lacking Fgf16

Emi Matsumoto, Sayaka Sasaki, Hideyuki Kinoshita, Takuya Kito, more

Genes to Cells > 18 > 7 > 544 - 553

Fibroblast growth factors (Fgfs) are pleiotropic proteins involved in development, repair and metabolism. Fgf16 is predominantly expressed in the heart. However, as the heart function is essentially normal in Fgf16 knockout mice, its role has remained unclear. To elucidate the pathophysiological role of Fgf16 in the heart, we examined angiotensin II‐induced cardiac hypertrophy and fibrosis in Fgf16...

article

HCN Channel Inhibition Prevents Sudden Arrhythmic Death in a Mouse Model of Dilated Cardiomyopathy Independently of Heart Rate Reduction

Yoshihiro Kuwabara, Koichiro Kuwahara, Makoto Takano, Hideyuki Kinoshita, more

Journal of Cardiac Failure > 2011 > 17 > 9 Supplement > S153

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INFONA - science communication portal

Search results for: Hideyuki Kinoshita

Fluorescence in situ hybridization‐negative intra‐articular myxoid liposarcoma with complex rearrangements involving EWSR1::DDIT3 detected using nanopore sequencing

Nanopore DNA Sequencing Detected Chromothripsis‐Induced PAFAH1B1::USP6 Rearrangement in Periosteal Solid Aneurysmal Bone Cyst Initially Diagnosed as Osteosarcoma

Metastasizing aneurysmal dermatofibroma initially diagnosed as angiosarcoma confirmed by CD63::PRKCD fusion gene detection with nanopore sequencing

Analysis of implants for metastatic bone tumors of the proximal femur: A retrospective study

Relationship between patient-based scoring systems and the activity level of patients measured by wearable activity trackers in lumbar spine disease

Successful total en bloc spondylectomy of the L3 vertebra with a paravertebral giant cell tumor following preoperative treatment with denosumab: a case report

Macro-pro-B-type natriuretic peptide (proBNP) and hidden macro-N-terminal proBNP: Case report

Acute Effects of Inhaled Iloprost in Pulmonary Arterial Hypertension Patients with Lung Disease

Clinical Features of the Systemic Sclerosis Associated Pulmonary Arterial Hypertension with Left Heart Disease

A Case of Macro-pro-B-Type Natriuretic Peptide (proBNP)

Outcomes of various transplant procedures (single, sparing, inverted) in living-donor lobar lung transplantation

Characteristic of Diagnostic Modalities and Corticosteroid Therapy in Cardiac Sarcoidosis

Surgical treatment for far-out syndrome associated with abnormal fusion of the L5 vertebral corpus and L4 hemivertebra: a case report

Role of O-glycosylation in N-terminal Region of Human proBNP in proBNP Processing

Pivotal Involvement of Renin-angiotensin System in Generating Arrhythmogenic Substrates in Mice with Chronic Heart Failure and Lethal Arrhythmias

Blockade of TRPC6 is a novel therapeutic approach against pathological cardiac remodeling

Evaluation of proBNP in End-stage Renal Disease Patients on Hemodialysis

Two Susceptibility Loci to Takayasu Arteritis Reveal a Synergistic Role of the IL12B and HLA-B Regions in a Japanese Population

Angiotensin II‐induced cardiac hypertrophy and fibrosis are promoted in mice lacking Fgf16

HCN Channel Inhibition Prevents Sudden Arrhythmic Death in a Mouse Model of Dilated Cardiomyopathy Independently of Heart Rate Reduction

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