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Polyurethanes containing z-lysine segments in the main chain (PULL) were synthesized from 4,4′-diphenylmethyl diisocyanate, poly(tetramethylene glycol), and z-lysine oligomer as a chain extender. The PULL film was treated first with a 10% HBr-acetic acid solution and subsequently with a saturated sodium bicarbonate aqueous solution to produce a primary amine group on the surface (PULL-N). Lactobionic...
Blood compatibilities of functional group-grafted and heparin-immobilized polyurethanes (PUs) were investigated using In vitro thrombus formation, plasma recalcification time (PRT), activated partial thromboplastin time (APTT), platelet adhesion and activation, and peripheral blood mononuclear cell (PBMC) activation. In the experiment with plasma proteins, PRT was shortened on amine group-grafted...
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