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Tools are limited in resolving the dynamic contributions of multicellular interactions in bioengineered tissues. In article number 1910442, Sangeeta N. Bhatia and co‐workers present CAMEO (controlled apoptosis in multicellular tissues for engineering organogenesis) as a strategy to precisely manipulate and study tissue composition. Herein, organoids comprised of hepatocytes (red) and fibroblasts (green)...
Engineered tissue models comprise a variety of multiplexed ensembles in which combinations of epithelial, stromal, and immune cells give rise to physiologic functions. Engineering spatiotemporal control of cell–cell and cell–matrix interactions within these 3D multicellular tissues would represent a significant advance for tissue engineering. In this work, a new method, entitled CAMEO (Controlled...
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