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Adrenal adenomas are incidentally identified in up to 5% of computer tomography scans performed for unrelated indications. A proportion of these adrenal incidentalomas are found to autonomously secrete cortisol based on definitions in current guidelines. Epidemiological studies suggest that chronic exposure to mild glucocorticoid excess from adrenal incidentalomas is associated with significantly...
Objectives
To assess the influence of a dietary sodium intake intervention on cortisol measurements within the general population.
Design
Cross‐over intervention.
Patients
Six hundred thirty adults without known Cushing syndrome, cardiovascular or renal disease completed a restricted dietary sodium diet (10 mmol/d, 230 mg/d) followed by cross‐over to a liberalized dietary sodium diet (200 mmol/d,...
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