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Summary. Treatment with hepatitis C virus (HCV)‐NS3‐protease inhibitors lead to the selection of resistant variants. Viral kinetics and resistance profiles in patients who are re‐treated with the same protease inhibitor are unknown. Viral kinetics and NS3‐resistance mutations obtained by clonal sequencing of the NS3‐protease were analyzed in nine HCV‐genotype‐1‐infected nonresponder patients who...
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