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The Unified Medical Language System (UMLS) is an important terminological system. By the policy of its curators, each concept of the UMLS should be assigned the most specific Semantic Types (STs) in the UMLS Semantic Network (SN). Hence, the Semantic Types of most UMLS concepts are assigned at or near the bottom (leaves) of the UMLS Semantic Network. While most ST assignments are correct, some errors...
The availability of Electronic Health Records (EHR) in health care settings provides terrific opportunities for early detection of patients' potential diseases. While many data mining tools have been adopted for EHR-based disease early detection, Linear Discriminant Analysis (LDA) is one of the most widely-used statistical prediction methods. To improve the performance of LDA for early detection of...
Well-designed and well-conducted clinical studies represent gold standard approaches for generating medical evidence. However, elderly populations are systematically underrepresented in studies across major chronic medical conditions, which has hampered the generalizability (external validity) of studies to the real-world patient population. It is the norm that intervention studies often require a...
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