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SARS‐CoV‐2 has developed a variety of approaches to counteract host innate antiviral immunity to facilitate its infection, replication and pathogenesis, but the molecular mechanisms that it employs are still not been fully understood. Here, we found that SARS‐CoV‐2 NSP8 inhibited the production of type I and III interferons (IFNs) by acting on RIG‐I/MDA5 and the signaling molecules TRIF and STING...
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