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AbstractAlthough the expression of 2,5-oligoadenylate synthetase (25AS) is induced by interferon (IFN), low constitutive levels can be detected in animals that have not been treated with IFN. In order to clarify which cells express 2-5AS in the mouse brain, the distribution of this enzyme in the brains of both normal healthy mice and mice treated with recombinant human IFN- A/D was studied by Western...
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