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TNFα, a proinflammatory cytokine, has been implicated in the pathogenesis of septic shock, viral myocarditis, and congestive heart failure. While the activated macrophage is thought to be the 1° source for TNFα production, a recent report showed that TNFα mRNA was expressed in the heart. However, the significance of this finding is not known. Accordingly, the purposeof this study was to determine:...
TNFα, a proinflammatory cytokine, has been implicated in the pathogenesis of septic shock, viral myocarditis, and congestive heart failure. While the activated macrophage is thought to be the 1° source for TNFα production, a recent report showed that TNFα mRNA was expressed in the heart. However, the significance of this finding is not known. Accordingly, the purposeof this study was to determine:...
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