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Although postictal events contribute to seizure severity and thus affect quality of life, the effect of antiepileptic drugs (AEDs) on the postictal state is not well known. This review assesses the available evidence from randomized controlled trials on the effect of AEDs on postictal events. The instruments used in AED trials include postictal items of The Liverpool Seizure Severity Scale (LSSS)...
Future directions for research need to include studies of the various experimental and clinical aspects of the postictal state. More specifically, we need reliable and validated instruments that are able to measure the beginning and the end of the postictal period. Although a number of questionnaires are available, we currently have no evidence that these tests are able to assess drug effects on the...
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