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We have shown previously that in addition to IL-4, IL-5 and IL-10, antigen-specific interferon-γ (IFN-γ) production by spleen cells from ovalbumin (OVA)/Alum-immunized mice is inhibited by the administration of royal jelly (RJ). Since it has been shown that both Th1 and Th2 cytokines play pathogenic roles in the generation of atopic dermatitis (AD), we have examined whether RJ suppresses the development...
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