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Virus detection and analysis are of critical importance in biological fields and medicine. Surface‐enhanced Raman scattering (SERS) has shown great promise in small molecule and even single molecule detection, and can provide fingerprint signals of molecules. Despite the powerful detection capabilities of SERS, the size discrepancy between the SERS “hot spots” (generally, <10 nm) and viruses (usually,...
In article 1805516, Shikuan Yang, Fubing Wang, Xiangheng Xiao, and co‐workers develop a volume‐enhanced Raman scattering substrate composed of hollow nanocones at the bottom of microbowls for the detection of viruses. The viruses captured by the nanocones are completely surrounded by the strong electromagnetic field, and greatly improved Raman signals of single viruses are demonstrated. This achievement...
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