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l-DOPA induced extracellular dopamine (DA), norepinephrine (NE) and serotonin (5-HT) in the ventromedial hypothalamus (VMH) of chickens were measured by in vivo microdialysis. Several doses of 3,4-dihydroxy-l-phenylalanine (l-DOPA) were administered locally through the microdialysis probe into the VMH of chickens for 10min. Local perfusion of l-DOPA increased the extracellular levels of DA. The increased...
Previous work from our laboratory suggests that ventromedial hypothalamic (VMH) dopamine levels were associated with decreased in food intake by chicken on a lysine-free diet. Dopamine in the VMH started to decrease from its baseline after presenting a lysine-free diet and subsequently food intake decreased. In the present study, the dopamine levels were manipulated by perfusing L-3-4-dihydroxyphenylalanine...
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