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Despite great advances in understanding the biological behaviors of chiral materials, the effect of chirality‐configured nanoparticles on tissue regeneration‐related biological processes remains poorly understood. Herein, the chirality of MoS2 quantum dots (QDs) is tailored by functionalization with l‐/d‐penicillamine, and the profound chiral effects of MoS2 QDs on cellular activities, angiogenesis,...
Metal aerogels represent an emerging type of functional porous materials with promising applications in diverse fields, but the fabrication of metal aerogels with specific structure and property still remains a challenge. Here, the authors report a new approach to fabricate metal aerogels by using ultrasmall metal nanoclusters (NCs) as functional building blocks. By taking D‐penicillamine‐stabilized...
A fundamental understanding of nanoparticle–protein corona and its interactions with biological systems is essential for future application of engineered nanomaterials. In this work, fluorescence resonance energy transfer (FRET) is employed for studying the protein adsorption behavior of nanoparticles. The adsorption of human serum albumin (HSA) onto the surface of InP@ZnS quantum dots (QDs) with...
Biological responses of cells and organisms to nanoparticle exposure crucially depend on the properties of the protein adsorption layer (“protein corona”) forming on nanoparticle surfaces and their characterization is a crucial step toward a deep, mechanistic understanding of their build‐up. Previously, adsorption of one type of model protein on nanoparticles was systematically studied in situ by...
FLIMaging nanoparticle degradation: semiconductor and metal nanoparticle degradation has been observed in live cells over 3 d via the change of the characteristic luminescence lifetime using fluorescence lifetime imaging microscopy (FLIM). Thus, FLIM is a simple yet robust tool to examine the intracellular stability of photoluminescent nanoparticles in live cells, tissues, and organisms.
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