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To evaluate the association of vitamin D levels and lower urinary tract symptoms (LUTS) among US men. Data were analyzed for 2387 men (≥20 years) who participated in the 2005-2006 cycle of the National Health and Nutrition Examination Survey, a cross-sectional survey of the US noninstitutionalized population. LUTS included nocturia, incomplete emptying, hesitancy, and urinary incontinence (UI)...
Nocturia, waking at night to void, is a common symptom in both men and women. The nocturia quality-of-life instrument, International Consultation on Incontinence Modular Questionnaire–Nocturia Quality of Life (ICIQ-Nqol), is the only current available, validated, symptom-specific tool for patients with nocturia. Because the ICIQ-Nqol was developed exclusively in men, the validity of its use in women...
To investigate the association between parity and exophytic bladder cancer growth in the UPII-SV40T transgenic mouse model of bladder cancer.The UPII-SV40T transgenic mice express the simian virus 40 large T antigen specifically in the urothelium (driven by uroplakin II promoter) and reliably develop bladder cancer. UPII-SV40T transgenic female mice were either never bred (nulliparous; n = 6) or placed...
To establish reliable noninvasive in vivo methods to detect, measure, and monitor experimentally induced urothelial tumors in mice. UPII-SV40T transgenic mice reliably develop bladder tumors by expression of simian virus 40 large T antigen specifically in bladder urothelium through the use of the uroplakin II promoter. Two wild-type and 10 UPII-SV40T transgenic mice were monitored for microhematuria...
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