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There are two major types of mouse xenograft models of cancer: subcutaneous implantation and orthotopic implantation. Subcutaneous transplant models are widely used with both cancer cell lines and human‐tumor specimens. Recently, subcutaneous models of patient tumors, termed patient‐derived xenographs (PDX) have become highly popular and have acquired such names as “Avatar” and “Xenopatients.” However,...
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