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Using computer-based tools, an interleukin (IL) 10 homologue has been identified from the puffer fish (Fugu rubripes) genome database. This is the first report on the existence of an IL-10 homologue in a non-mammalian vertebrate species. The Fugu IL-10 gene is located within a 2790-bp fragment including 549bp of coding sequence which translates into an 183-amino-acid protein. It is predicted to contain...
Abstract. The full-length sequence of a second IL-1 gene (IL-12) in rainbow trout (Oncorhynchus mykiss) has been obtained. As with the first IL-1 gene, IL-12 is organized into six exons/five introns. There are only small differences in their intron/exon sizes, with the exception of intron 3, which is 334bp smaller in IL-12. The transcript encoded by the IL-12 gene contains a 5 untranslated region...
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